Asin Thottumkal was born in October 26, 1985. she born into a Syro Malabar, Syrian Christian family in Kochi, Kerala. Her father, Joseph Thottumkal originally from Thodupuzha, managed several businesses and was considered a prominent entrepreneur before he stopped managing his businesses and decided to manage his daughter's acting career instead. Furthermore Asin's father accompanies her to all her foreign shoots. Her mother, Seline Thottumkal, remains a surgeon despite moving settlements from Cochin to Chennai to Mumbai to live with her daughter.
Asin has quoted that her name "means pure and without blemish". She claims that "the 'A' in her name is from Sanskrit meaning "without", and ‘Sin’ from English".
Now, She is currently considered to be one of the most popular actresses in the South Indian film industry. Making her acting debut in Sathyan Anthikkad's Narendra Makan Jayakanthan Vaka (2001), Asin had her first commercial success with Amma Nanna O Tamila Ammayi in 2003, and won a Filmfare Award for the Best Telugu Actress for the film.
After a number of films, she received her second South Filmfare Award for Best Actress for her performance in her second Tamil film, Ghajini (2005). She played the lead female roles in hits, the thriller Ghajini (2005) and the action comedy Varalaru (2006). More recently, Asin made her début in Bollywood, with Ghajini, the remake of its Tamil namesake, subsequently winning the Filmfare Best Female Debut Award Award.